Analysis of Neisseria Meningitidis carriage characteristics among healthy population in Shandong province from 2008 to 2020
10.3760/cma.j.cn112150-20210412-00358
- VernacularTitle:2008—2020年山东省健康人群脑膜炎奈瑟菌携带特征分析
- Author:
Yan ZHANG
1
;
Manshi LI
;
Guifang LIU
;
Xiaojuan LIN
;
Lei FENG
;
Aiqiang XU
;
Li ZHANG
Author Information
1. 山东省疾病预防控制中心免疫预防管理所 山东大学预防医学研究院 山东省传染病预防控制重点实验室，济南250014
- Keywords:
Epidemic cerebrospinal meningitis;
Neisseria meningitides;
Serotyping;
Healthy population
- From:
Chinese Journal of Preventive Medicine
2021;55(8):973-977
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the carriage characteristics of Neisseria meningitidis ( Nm) among healthy population of epidemic cerebrospinal meningitis in Shandong province. Methods:From April 2008 to April 2020, a total of 16 848 healthy population were recruited from Lixia District of Jinan City, Gaomi City of Weifang City, Jiaxiang County of Jining City, Wendeng District of Weihai City, Tancheng County of Linyi City and Linyi County of Dezhou City for the investigation.Throat swab samples were collected, Nm was isolated, cultured and identified, and Nm carrying characteristics of healthy population with different characteristics were analyzed. Results:Among the 16 848 healthy population, male accounted for 51.86% (8 737). A total of 136 Nm strains were isolated, and the carriage rate was 0.81%. Among the 136 Nm strains, serogroup B (60.29%) and ungroupable strains (23.53%) were dominant. Analysis of the Nm carriage rate, that were higher in the healthy population of Linyi (1.39%) and Jinan (1.14%), higher in 13-16 years old (1.60%) and 17-19 years old (1.10%) healthy population, and higher in male (1.02%). Conclusion:The Nm carriage rate of healthy population is relatively low in Shandong Province, and the proportion of serogroup B and ungroupable Nm is relatively high.
