Short-term outcomes of lung transplant recipients using organs from brain death donors
10.3760/cma.j.issn.0529-5815.2016.12.004
- VernacularTitle:脑死亡供者肺移植近期预后分析
- Author:
Wenxin HE
1
;
Chao JIANG
;
Xiaogang LIU
;
Wei HUANG
;
Chang CHEN
;
Lei JIANG
;
Bei YANG
;
Kun WU
;
Qiankun CHEN
;
Yang YANG
;
Yongmei YU
;
Gening JIANG
Author Information
1. 200433,同济大学附属上海市肺科医院胸外科
- Keywords:
Lung transplantation;
Brain death;
Treatment outcome
- From:
Chinese Journal of Surgery
2016;54(12):894-897
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess short?term outcomes after lung transplantation with organs procured following brain death?Methods Between April 2015 and July 2016, all 17 recipients after lung transplantation using organs from brain death donors ( DBD) at Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine were enrolled in this study? All patients were male, aging (60±7) years, including 11 chronic obstructive pulmonary disease, 5 idiopathic pulmonary fibrosis, 1 silicosis. Seventeen donors were 16 males and 1 female, with 10 traumatic brain injury, 5 cerebrovascular accident and 2 sudden cardiac death? Of 17 recipients receiving DBD lung transplant, 16 were single lung transplant? Data were collected including intubation duration of mechanical ventilation, hospital length of stay, incidence of pulmonary infection bronchus anastomosis complications, primary graft dysfunction (PGD), and acute rejection, bronchiolitis obliterans syndrome (BOS) as well as mortality of 90?day after lung transplantation? Results Median duration of intubation were 2 (2) days (M(QR)) in recipients after lung transplantation? The incidence of pulmonary infection and bronchus anastomosis complications were 15/17 and 5/17, respectively? Median length of stay in hospital were 56 ( 19) days? The ratio of readmission 1 month after discharge were 10/17? Mortality of 90?day post?transplant were 2/17? The incidence of PGD and BOS were 1/17 and 2/17, respectively?Conclusion Recipients with DBD lung transplantation have an acceptable survival during short?term follow?up, but with higher incidences of complications related to infection post?transplantation.
