New Forms of Material Basis for Traditional Chinese Medicine and Their Pharmacokinetics/Pharmacodynamics Study
10.14148/j.issn.1672-0482.2024.1013
- VernacularTitle:中药物质基础新形式及其药动/药效研究
- Author:
Xuan HUI
1
;
Jingyan ZHANG
;
An KANG
;
Jingwei ZHANG
;
Guangji WANG
Author Information
1. 中国药科大学江苏省药物代谢动力学研究重点实验室,中国医学科学院"中药复杂组分PK-PD结合研究"创新单元,江苏南京 210009
- Keywords:
traditional Chinese medicine;
new forms of material basis;
supramolecules;
bio-macromolecules;
pharmacokinetics/pharmacodynamics
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2024;40(10):1013-1023
- CountryChina
- Language:Chinese
-
Abstract:
Traditional Chinese medicine,as a treasure of the Chinese nation,has a long history and rich cultural connotations.O-ver the past few hundred years,a large number of active compounds with clear structure,significant activity and elucidated mechanism have been discovered.Their research constitutes the material basis for traditional Chinese medicine research.However,the natural components of traditional Chinese medicine have diverse skeletons and complex structures.In addition to small molecule monomer com-pounds,more and more recent studies have found that there are new forms of material basis for traditional Chinese medicines to exert their pharmacological effects,such as supramolecules formed by active monomer compounds,and bio-macromolecules with pharmaco-logical activity.This article focuses on new forms of the material basis of traditional Chinese medicine,and through analysis of new technologies,mechanisms,and applications,it aims to provide new ideas for research on the material basis of efficacy in traditional Chinese medicine and its pharmacokinetic/pharmacodynamic correlation.
