Lignans and Phenolic Compounds from Asparagus Gobicus
10.14148/j.issn.1672-0482.2016.0291
- VernacularTitle:戈壁天冬中的木脂素和酚酸类化学成分
- Author:
Cui MA
1
;
Juan LI
;
Huai-Qin HAN
;
Nan LI
;
Ping ZHENG
;
Jing ZHAO
;
Wei-Qi LI
;
Yao YAO
Author Information
1. 宁夏医科大学基础医学院
- Keywords:
Asparagus gobicus;
chemical constituents;
lignans;
phenolic compounds
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2016;32(3):291-294
- CountryChina
- Language:Chinese
-
Abstract:
ABSTRACT:OBJECTIVE To study the chemical constituents of Asparagus Gobicus .METHODS Whole herb of Asparagus gobicus were extracted with 95% alcohol.Repeated silica gel column chromatography,Sephadex LH-20 chromatography,pre-parative HPLC and thin layer chromatography were applied for chemical constituents isolation and purification.Chemical struc-tures of the compounds were elucidated by physical properties and spectra analysis such as NMR and ESI-MS.RESULTS Nine compounds were isolated from the extract of Asparagus gobicus .Six compounds were identified as lignans:(+)-pinoresinol (1),(-)-syringaresinol(2),(+)-syringaresinol-4'-O-β-D-glucopyranoside(3),(-)-episyringaresinol(4),(+)-nyasol(5), (+)-4'-O-methylnyasol(6).Three compounds were phenolic compounds:ferulic acid(7),isoferulic acid(8),caffeic acid(9). CONCLUSION All compounds were isolated for the first time from this plant,and compounds 1~4 and 8 were obtained from the genus Asparagus for the first time.
