Effects of occupational nickel exposure on glycemic parameters in workers
10.3760/cma.j.cn121094-20190927-00405
- VernacularTitle:职业性镍接触对作业工人血糖相关指标的影响
- Author:
Xin LIU
1
;
Lixin ZHONG
;
Dong JIANG
;
Yang CHEN
;
Wei GONG
;
Min LV
Author Information
1. 210028 南京，江苏省疾病预防控制中心职业病防治所
- Keywords:
Nickel;
Occupational exposure;
Blood nickel;
Fasting blood glucose;
Fasting insulin;
Glycosylated hemoglobin
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2020;38(11):843-845
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effect of occupational nickel exposure on blood glucose related indicators of workers.Methods:In March 2019, five electroplating enterprises and one plastic hardware enterprise were selected by cluster sampling method. 159 nickel plating workers were selected as the contact group, and 66 administrative personnel of the same enterprise were selected as the control group. The serum nickel concentration, fasting blood glucose (FPG) , fasting insulin (FIns) and glycosylated hemoglobin (HbA1c) were measured in the contact group and the control group. The differences of blood glucose related indexes between the two groups were compared, and the risk factors of abnormal blood glucose indexes were analyzed.Results:Compared with the control group, the blood nickel concentration and detection rate of nickel in the contact group were higher, the levels of FIns were lower, and the proportion of HbA1c was higher in the contact group ( P<0.05) . Stratified analysis showed that compared with the control group, the blood glucose index of men in the contact group changed significantly ( P<0.05) ; logistic regression analysis showed that male was an independent influencing factor for decreased FIns ( OR=8.264, P<0.05) . Conclusion:Long term exposure to nickel can affect the blood glucose related indexes such as fins and HbA1c.
