Radiotherapy forgynecologic cancer innonagenarian patients：a framework fornew paradigms
- Author:
BenoteMry
1
;
SylvieMengueNdong
;
JeanBaptisteGuy
;
AviAssouline
;
AlexanderTFalk
;
AnasValeille
;
JaneChloTrone
;
RomainRivoirard
;
PierreAuberdiac
;
AlexisVallard
;
SophieEspenel
;
GuillaumeMoriceau
;
OlivierCollard
;
ClaireBosacki
;
JeanPhilippeJacquin
;
GuydeLaroche
;
PierreFournel
;
CyrusChargari
;
Magn NICOLAS
Author Information
- Keywords: Gynecologic cancer; Nonagenarians; Female genital tract; Radiotherapy; Geriatrics
- From:Chinese Journal of Cancer 2016;35(7):382-385
- CountryChina
- Language:Chinese
- Abstract: No consensus exists regarding the role of radiotherapy in the management of gynecologic cancer in nonagenar?ian patients. We retrospectively reviewed the outcomes of 19 consecutive nonagenarian patients with gynecologic cancer (6 endometrial cancers, 6 cervical cancers, 4 vulvar cancers, and 3 vaginal cancers) who were treated with radiotherapy. Radiotherapy was performed mainly in a palliative setting (n=12; 63.2%), with a median dose of 45Gy (range, 6–76Gy). Infrequent major acute or late toxicities were reported. Among 19 patients, 9 (47.4%) experienced tumor progression, 5 (26.3%) experienced complete response, 2 (10.5%) experienced stable disease and/or partial response. At last follow?up, 12 patients (63.2%) had died; most deaths (n=9) occurred because of the cancer. These results suggest that radiotherapy is feasible in the treatment of nonagenarian patients with gynecologic cancer.
