Differentiation therapy：a promising strategy forcancer treatment
10.1186/s40880-015-0059-x
- Author:
MinYan
1
;
QuentinLiu
Author Information
1. State Key Laboratory of Oncology in South China
- Keywords:
Differentiation therapy;
Cancer treatment;
IkB kinase α
- From:Chinese Journal of Cancer
2016;(1):4-7
- CountryChina
- Language:Chinese
-
Abstract:
Poor differentiation is an important hallmark of cancer cells, and differentiation therapy holds great promise for cancer treatment. The restoration of IkB kinase α (IKKα) leads to the differentiation of nasopharyngeal carcinoma cells with reduced tumorigenicity. The ifndings by Yan etal. validate the polycomb protein enhancer of zeste homologue 2 (EZH2) as a target for intervention.
