Impact of live attenuated rotavirus vaccines on the mutation and evolution of rotavirus epidemic strains
10.3760/cma.j.cn112866-20230710-00073
- VernacularTitle:轮状病毒减毒活疫苗的使用对轮状病毒流行的影响
- Author:
Mengjie DONG
1
;
Dandi LI
Author Information
1. 中国疾病预防控制中心病毒病预防控制所 国家卫生健康委员会医学病毒和病毒病重点实验室,北京 102206
- Keywords:
Rotavirus;
Genotype;
Live attenuated vaccine
- From:
Chinese Journal of Experimental and Clinical Virology
2023;37(6):664-669
- CountryChina
- Language:Chinese
-
Abstract:
The live attenuated rotavirus vaccine has been recommended by the World Health Organization for inclusion in national immunization plans since 2009. Several countries around the world have included RotaTeq and Rotarix vaccines in their national immunization plans. However, after large-scale vaccination, changes in the dominant genotype of rotavirus have been found in multiple countries, but different trends have emerged in different regions. The purpose of this study was to investigate whether rotavirus vaccine has an impact on genotype change.