Association of NMDAR, NR2A, and NR2B with cognitive impairment in diabetic patients

VernacularTitle:NMDAR、NR2A、NR2B与糖尿病认知功能障碍的关系
Author: Xiaopeng WANG ¹ ; Yongjie HUANG ; Fang WANG ; Yingying ZOU
Author Information

1. 昆明医科大学基础医学院病理学与病理生理学系
Keywords: diabetes; cognitive impairment; N-methyl-D-aspartame receptor; NR2A; NR2B
From: Journal of Southern Medical University 2013;(12):1848-1851
CountryChina
Language:Chinese
Abstract: Cognitive impairment in diabetes (CID) is a severe chronic complication of diabetes mellitus, and its pathogenesis has not yet been fully understood. Increasing evidence has shown that the distribution and expression of N-methyl-D-aspartame receptor (NMDAR) and subunits NR2A and NR2B, which all participated in the development of the central nervous system and formation of learning and memory, are correlated with the occurrence and development of CID.