Interpretation of the group standard for Standard strains of pathogenic microorganism-technical specifications for establishment of HIV strains
10.3760/cma.j.cn112866-20230609-00059
- VernacularTitle:病原微生物菌(毒)种标准株 艾滋病病毒毒株建立技术规范团体标准解读
- Author:
Chuntao MA
1
;
Qiang WEI
;
Yan JIANG
Author Information
1. 中国疾病预防控制中心性病艾滋病预防控制中心，北京 102206
- Keywords:
Human immunodeficiency virus;
Standard strains;
Group standard;
Technical specification;
Biosafety
- From:
Chinese Journal of Experimental and Clinical Virology
2023;37(3):265-270
- CountryChina
- Language:Chinese
-
Abstract:
Human immunodeficiency virus (HIV) strains are important national biological resources, and the establishment of HIV standard strains forms material basis for HIV diagnostic testing, epidemic surveillance, disease prevention and control, reagent evaluation, drug research and vaccine development. The National Center for AIDS/STD Control and Prevention of China took the lead in development and publication of the Chinese Preventive Medicine Association (CPMA) group standard, Standard strains of pathogenic microorganism-technical specifications for establishment of HIV strains (T/CPMA 027—2023). Published on February 2, 2023, the standard, for the first time, specifies all technical requirements for establishment of HIV standard strains, covering sampling, isolation, culture, titration, identification, evaluation, preservation, archiving, quality control and biosafety management, and it also standardizes HIV isolation and characterization procedure, and relevant information description. This paper provides in-depth views on development of HIV standard strains, formulation and application of relevant standards, in order to pave solid ground for establishment of HIV standard strain banks and improvement of repository quality control, utilization and biosafety management.
