Associations of cardiometabolic multimorbidity with grip strength and gait speed among older Chinese adults
10.3760/cma.j.cn112338-20230108-00015
- VernacularTitle:中国老年人心血管代谢性共病与握力和步速关系的队列研究
- Author:
Huiwen XU
1
;
Yuming CHEN
;
Zhou YANG
;
Yonghua HU
;
Beibei XU
Author Information
1. 北京大学公共卫生学院流行病与卫生统计学系，北京 100191
- Keywords:
Cardiometabolic multimorbidity;
Grip strength;
Gait speed;
Older adults
- From:
Chinese Journal of Epidemiology
2023;44(8):1183-1189
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the associations of cardiometabolic multimorbidity (CMM) with grip strength and gait speed among older Chinese adults.Methods:This study included participants aged ≥60 years from the China Health and Retirement Longitudinal Survey during 2011-2015. Generalized estimating equation models were employed to estimate the associations of CMM with grip strength and gait speed.Results:A total of 6 357 participants were included to measure grip strength and 6 250 participants to measure gait speed. Compared with no cardiometabolic disease, participants with 1 ( β=-0.018, 95% CI: -0.026--0.010), 2 ( β=-0.029, 95% CI: -0.041- -0.018), and ≥3 ( β=-0.050, 95% CI: -0.063- -0.037) cardiometabolic diseases were associated with a decreased grip strength. The associations between cardiometabolic disease counts (1: β=-0.052, 95% CI: -0.326 -0.222; 2: β=-0.083, 95% CI: -0.506 -0.340; ≥3: β=-0.186, 95% CI: -0.730 -0.358) and gait speed were not statistically significant. The predictive value of gait speed of the participants with 0, 1, 2, and ≥3 cardiometabolic diseases were found to be 1.98 (95% CI: 1.38-2.58), 1.93 (95% CI: 1.34-2.51), 1.89 (95% CI: 1.18-2.61), and 1.79 (95% CI: 1.10-2.48) m/s respectively, which was clinically significant for the magnitude of the decrease. Cardiometabolic combinations with a higher risk of decreased grip strength and gait speed mainly seen in diabetes. Conclusions:Cardiometabolic disease counts and combinations were associated with grip strength and gait speed. Grip strength and gait speed can be used to measure CMM severity.
