The study of countermeasures on measles control in infants

VernacularTitle:小月龄婴儿麻疹发病控制对策探讨
From: Chinese Journal of Epidemiology 2001;22(1):49-50
CountryChina
Language:Chinese
Abstract: Objective　To understand: a) measles antibody levels in puerpera and their newborns, and the relation between them， b) maternal transferred measles antibody level of different age group infants, c) immunization rates of success in 6 and 8 month old infants, d) to study measles control countermeasures on infants. Method　To test measles IgG antibody levels of infant's blood using ELISA method. Results　Antibody levels of measles in 58 pairs of mother and their newborns, 51 pairs were the same, while 7 pairs were different. Measles antibody levels in newborns was not high and reduced to 50% in 3 months, 20% in 6 months, and 15% in 8 months. The antibody levels in 6 and 8 month olds were low, nearly no protection to children. It was found that rates of immunization success and the antibody distribution were not statistically different between 6 and 8 months olds after measles vaccination. Conclusion　It was found that the measles antibody level in most matured women was low. Since mother's measles antibody level has close relation to their newborns, it seems that the newborn's antibody level can be improved by vaccination to matured women. In order to reduce morbidity of infant measles, the age of first vaccination of measles vaccine should be changed from 8 months old to 6 months old in some regions.