Exosomes-based strategies for dental pulp regeneration

VernacularTitle:基于外泌体的牙髓再生策略
Author: Yan CHEN ¹ ; Xueting YANG ; Yue MA ; Bo YANG ; Weidong TIAN
Author Information

1. 四川大学华西口腔医院创伤整形外科　口腔疾病研究国家重点实验室　国家口腔疾病临床医学研究中心　口腔转化医学教育部工程中心　口腔再生医学国家地方联合工程实验室，成都　610041
Keywords: Dental pulp; Stem cells; Pulp regeneration; Dental stem cells; Exosomes
From: Chinese Journal of Stomatology 2021;56(7):709-714
CountryChina
Language:Chinese
Abstract: Researches on pulp regeneration based on odontogenic stem cells have made a breakthrough and some results have been applied clinically in recent years. It is demonstrated that exosomes secreted by stem cells play a significant role in tissue regeneration. Compared with stem cells, exosomes exhibit more advantages such as wider sources, more immediate effects, and less immune rejections, which are expected to be exploited in the pulp regeneration by cell-homing. In this review, the conventional dental pulp tissue engineering and exosomes-based dental pulp regeneration method are discussed, the new strategy for dental pulp regeneration by using exosomes is analyzed and proposed.