Research progress of the relationship between Candida albicans and dental caries
10.3760/cma.j.cn112144-20200609-00324
- VernacularTitle:白色念珠菌与龋病相关性的研究进展
- Author:
Xiaohui LYU
1
;
Kun WANG
;
Linglin ZHANG
Author Information
1. 四川大学华西口腔医院牙体牙髓病科 口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心 四川大学华西口腔医学院实验教学示范中心,成都 610041
- Keywords:
Candida albicans;
Dental caries;
Streptococcus mutans;
Microbial interactions;
Oral microbiota
- From:
Chinese Journal of Stomatology
2021;56(5):491-496
- CountryChina
- Language:Chinese
-
Abstract:
Candida albicans (Ca) is an important opportunistic pathogenic fungus found in the oral cavity, which plays an important role in oral microecological balance, and often interacting with other bacteria including Streptococcusmutans (Sm). Meanwhile, the characteristics of Ca such as adhesion, acidogenicity, aciduric nature and the ability to produce collagenolytic proteinases indicate its latent cariogenic potential. This review summarizes the research progress of the detectable rate of Ca in caries, its cariogenic potential and the interaction with Sm and other oral bacteria, in order to extend the understanding of pathogenesis of dental caries and to contribute new therapeutic and preventive strategies for dental caries.