Research status of chemical constituents,pharmacological effects and predictive analysis of quality markers of Hedyotis diffusa

VernacularTitle:白花蛇舌草化学成分、药理作用、质量标志物预测的研究现状
Author: Ying-Jie WANG ¹ ; Hui-Quan HU ; Qian WU ; Jia-Mei ZOU ; Yu-Hui PING
Author Information

1. 江西中医药大学药学院,江西南昌 330004
Keywords: Hedyotis diffusa; chemical composition; pharmacological effect; quality marker
From: The Chinese Journal of Clinical Pharmacology 2024;40(15):2296-2300
CountryChina
Language:Chinese
Abstract: Hedyotis diffusa has unique therapeutic effects on snake and insect bites,edema,cancer and other diseases,and is widely used clinically.However,the《Chinese Pharmacopoeia》has no record of the name of the plant,and there is no fundamental basis for its elaboration of the relationship between"composition-potency-quality marker(Q-Marker)".This article reviews the chemical constituents and pharmacological effects of Hedyotis diffusa,and combined with the concept of Q-Marker.Q-Marker predictions were made in terms of traditional efficacy,traditional medicinal properties and the measurability of chemical components,in order to provide a reference for the clinical applications,quality evaluation further studies of Hedyotis diffusa in the future.