Research status of traditional Chinese medicine regulation of mitochondrial autophagy in the treatment of cerebral ischemia-reperfusion injury

VernacularTitle:中药调控线粒体自噬治疗脑缺血再灌注损伤的研究现状
Author: Guan-Hua LI ¹ ; Yue-Hui MA ; Zhe-Yi ZHOU
Author Information

1. 广西中医药大学研究生学院,广西壮族自治区南宁 530200;柳州市中医医院神经内科,广西壮族自治区柳州 545002
Keywords: Chinese medicine; mitophagy; cerebral ischemia-reperfusion injury; research status
From: The Chinese Journal of Clinical Pharmacology 2024;40(15):2273-2277
CountryChina
Language:Chinese
Abstract: Mitophagy has a neuroprotective role in cerebral ischemia/reperfusion(I/R)injury,and the regulation of mitophagy may be an important target for the treatment and improvement of prognosis of cerebral ischemia.In recent years,traditional Chinese medicine(TCM)has developed rapidly,and due to its advantages of fewer side effects,significant curative effect,and multiple targets,the regulation of mitophagy by traditional Chinese medicine to improve I/R has become a research hotspot.This article summarizes the important research progress of TCM monomers and TCM compounds in regulating mitophagy in the treatment of I/R injury in recent years,so as to provide research basis and theoretical guidance for the research on the relationship between TCM and mitophagy in I/R injury.