Research status of quercetin-mediated MAPK signaling pathway in prevention and treatment of osteoporosis
10.13699/j.cnki.1001-6821.2024.09.029
- VernacularTitle:槲皮素介导MAPK信号通路防治骨质疏松的研究现状
- Author:
Ke-Xin YUAN
1
;
Xing-Wen XIE
;
Ding-Peng LI
;
Yi-Sheng JING
;
Wei-Wei HUANG
;
Xue-Tao WANG
;
Hao-Dong YANG
;
Wen YAN
;
Yong-Wu MA
Author Information
1. 甘肃中医药大学中医临床学院,甘肃兰州 730000
- Keywords:
Quercetin;
osteoporosis;
mitogen-activated protein kinase signaling pathway;
osteoblast;
osteoclast
- From:
The Chinese Journal of Clinical Pharmacology
2024;40(9):1375-1379
- CountryChina
- Language:Chinese
-
Abstract:
Quercetin can mediate the activation of mitogen-activated protein kinase(MAPK)signaling pathways to prevent osteoporosis(OP).This paper comprehensively discusses the interrelationship between MAPK and osteoporosis-related cells based on the latest domestic and international research.Additionally,it elucidates the research progress of quercetin in mediating the MAPK signaling pathway for OP prevention.The aim is to provide an effective foundation for the clinical prevention and treatment of OP and the in-depth development of quercetin.