Research status on the regulation of endogenous sulfur dioxide on blood vessels

VernacularTitle:内源性二氧化硫对血管的调控作用研究现状
Author: Yun-Jia SONG ¹ ; Qing ZHONG ; Rong ZHANG ; Xu-Tao SUN
Author Information

1. 黑龙江中医药大学基础医学院,黑龙江哈尔滨 150040
Keywords: sulfur dioxide; blood vessel; high blood pressure; pulmonary hypertension; atherosclerosis
From: The Chinese Journal of Clinical Pharmacology 2024;40(7):1085-1088
CountryChina
Language:Chinese
Abstract: Sulfur dioxide(SO2)is involved in regulating various physiological processes of blood vessels,such as maintaining normal vascular structure,regulating vascular tension,controlling blood pressure,inhibiting vascular cell proliferation,regulating apoptosis and autophagy.In pathophysiological conditions such as hypertension,pulmonary hypertension and atherosclerosis,SO2 plays a protective role in pathological changes through different molecular mechanisms.In this paper,we will review the endogenous SO2 production and metabolism,vascular biological effects and its regulation on blood vessels.