Introduction of animal model of dysmenorrhea
10.13699/j.cnki.1001-6821.2024.07.029
- VernacularTitle:痛经动物模型的介绍
- Author:
Meng-Jie TANG
1
;
Zhi LIAO
Author Information
1. 电子科技大学医学院,四川成都 611731
- Keywords:
dysmenorrhea;
animal model;
estradiol;
oxytocin;
evaluation index;
prostaglandin;
nitric oxide
- From:
The Chinese Journal of Clinical Pharmacology
2024;40(7):1072-1075
- CountryChina
- Language:Chinese
-
Abstract:
Dysmenorrhea is one of the most common gynecological symptoms with a high incidence,but its pathogenesis is complex.Animal models play an important role in the pathogenesis and clinical prevention and treatment of dysmenorrhea.The most common modeling method is estradiol+oxytocin induction.This paper not only evaluated the models from the aspects of behavior,tissue and biochemistry,but also reviewed the application progress and evaluation analysis of dysmenorrhea models in the past 15 years,in order to provide ideas for the preparation and evaluation analysis of animal models
