Research progress of biological targeted therapy for atopic dermatitis

VernacularTitle:特应性皮炎生物靶向治疗研究发展
Author: Ying LIU ¹ ; Cai-Jun YAO ; Hui ZENG ; Ji-Fang CHEN ; Chun ZHOU
Author Information

1. 广州新华学院药学院,广东广州 510520
Keywords: atopic dermatitis; biological agents; targeted therapy; clinical trial
From: The Chinese Journal of Clinical Pharmacology 2024;40(5):768-772
CountryChina
Language:Chinese
Abstract: Atopic dermatitis(AD)is the most common chronic inflammatory skin disease.For decades,the treatment of AD has been limited to local corticosteroid or calcineurin inhibitors,and light therapy or systemic immunosuppressive drug for moderate to severe AD patients.With the in-depth study of the pathogenesis of AD,many local and systemic targeted therapy drugs are being developed,which may change the treatment options of AD.This review combination with the latest clinical trials give a summarize on the type,mechanism,efficacy and safety of biological targeted therapy for AD,to provide a theoretical basis for the individualized treatment of AD.