Clinical characteristics and treatment analysis of patients with moderate hyponatremia
10.13699/j.cnki.1001-6821.2024.03.010
- VernacularTitle:中度低钠血症患者的临床特点及治疗分析
- Author:
Qing CHEN
1
;
Yu-Miao LI
;
Yan JIANG
;
Ai-Wen HUANG
Author Information
1. 福建医科大学福总临床医学院,福建福州 350025;中国人民解放军联勤保障部队第九○○医院临床药学科,福建福州 350025
- Keywords:
concentrated sodium chloride injection;
moderate hyponatremia;
clinical characteristics;
treatment;
general surgery
- From:
The Chinese Journal of Clinical Pharmacology
2024;40(3):350-353
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical characteristics of patients with moderate hyponatremia in general surgery and analyze the efficacy.Methods Patients with moderate hyponatremia in general surgery were divided into control group(without supplemented concentrated sodium chloride injection)and treatment group(supplemented concentrated sodium chloride injection)according to the cohort method.The clinical characteristics of patients with moderate hyponatremia,such as gender distribution,age distribution,nutritional status,and primary disease were analyzed.Propensity score matching(PSM)was performed to balance confounding factors between the two groups,making their baseline conditions comparable and comparing the differences in clinical outcomes between the two groups.Results A total of 227 cases were included,including 82 in the control group and 145 in the treatment group.The predisposing factors of moderate hyponatremia in general surgery patients include male,elderly,malnutrition,parenteral nutrition,and malignant tumors.In addition,after PSM,there were 73 patients in each group of the control group and treatment group with moderate hyponatremia.The total effective rate of the control group was 80.82％,and correction of the hyponatremia takes time was(3.97±2.54)The total effective rate of the treatment group was 98.63％,and correction of the hyponatremia takes time was(3.54±1.90)d.The differences were statistically significant(all P＜0.05).Conclusion We should pay more attention to patients with moderate hyponatremia in general surgery,and be alert to the risk of severe hyponatremia.For patients with moderate hyponatremia,concentrated sodium chloride injection should be given to improve efficacy and prognosis.
