Research status on establishment of collateral circulation and therapy in ischemic stroke
10.13699/j.cnki.1001-6821.2024.02.027
- VernacularTitle:缺血性脑卒中的侧支循环建立及治疗的研究现状
- Author:
Jin SUN
1
;
Li-Chen GUO
;
Meng WANG
;
Lin-Lin SU
;
Qing YUAN
;
Li-Min HU
Author Information
1. 天津中医药大学组分中药国家重点实验室、方剂学教育部重点实验室、天津市中药药理学重点实验室,天津 301617
- Keywords:
ischemic stroke;
collateral circulation;
clinical significance;
treatment
- From:
The Chinese Journal of Clinical Pharmacology
2024;40(2):279-283
- CountryChina
- Language:Chinese
-
Abstract:
Intravenous thrombolysis and revascularisation are subject to strict time windows,and most patients still need to reperfuse ischaemic tissue through their own compensatory mechanisms due to subsequent re-occlusion or"no-reflow".A good collateral circulation can prolong the therapeutic window,increase the tolerance of brain tissue to ischaemia and hypoxia,and improve the prognosis,so promoting the establishment of collateral circulation to improve ischaemic tissue perfusion is a new idea in the treatment of ischaemic stroke.In this paper,we provides a review of relevant studies on methods of assessment of collateral circulation,therapeutic approaches,and clinical significance to provide guidance for the treatment of ischaemic stroke.
