Pharmacokinetic study and clinical application of tigecycline
10.13699/j.cnki.1001-6821.2023.24.028
- VernacularTitle:替加环素的药代动力学/药效学研究与临床应用
- Author:
Xi-Wei JI
1
;
Xu-Zhu MA
;
Jing DONG
;
Xiang-Rui MENG
Author Information
1. 北京大学第一医院临床药理研究所,北京 100191
- Keywords:
tigecycline;
pharmacokinetics;
pharmacodynamics;
clinical application
- From:
The Chinese Journal of Clinical Pharmacology
2023;39(24):3674-3676
- CountryChina
- Language:Chinese
-
Abstract:
As the first glycylcycline used in clinical,tigecycline has ultra broad-spectrum antibacterial activity,which exerts good antibacterial effects on gram-positive or negative aerobic bacteria,anaerobic bacteria,especially pan drug resistant pathogens,and atypical pathogens.This article provides a brief overview of the pharmacokinetic and pharmacodynamic study of tigecycline and reviews the latest developments in its clinical applications.