Research advances in traditional Chinese medicine for the treatment of hepatocellular carcinoma by regulating immune cells
- VernacularTitle:中药调控免疫细胞治疗肝细胞癌的研究进展
- Author:
Lijuan LONG
1
;
Zongyu WANG
2
;
Yali ZHAO
1
;
Chuanfu QIN
3
;
Hua QIU
2
Author Information
- Publication Type:Review
- Keywords: Carcinoma， Hepatocellular; Immune Cells; Immunosuppression; Traditional Chinese Drugs
- From: Journal of Clinical Hepatology 2025;41(2):349-358
- CountryChina
- Language:Chinese
- Abstract: Hepatocellular carcinoma （HCC） is a common malignant tumor with a high mortality rate， an insidious onset， and complex pathological mechanisms. In the tumor microenvironment， tumor-promoting immune cells protect tumor cells from immune attacks， while dysfunction of anti-tumor immune cells causes the inhibition of immune response， thereby leading to the continuous deterioration of cancer. In recent years， traditional Chinese medicine has shown good efficacy in the treatment of HCC， and it can inhibit the proliferation and metastasis of cancer cells by regulating immune cells. By analyzing related articles in China and globally， this article summarizes how immune cells affect the progression of HCC through the immunosuppressive pathway and how traditional Chinese medicine exerts an anti-HCC effect by regulating immune cells， in order to provide theoretical basis and reference for optimizing the treatment of HCC.
