Diagnostic efficacy of dynamic contrast-enhanced magnetic resonance imaging combined with diffusion-weighted imaging for prostate cancer
- VernacularTitle:动态增强磁共振成像联合弥散加权成像对前列腺癌的诊断效能
- Author:
Yuanfei ZHANG
1
Author Information
- Publication Type:Research Article
- Keywords: dynamic contrast-enhanced magnetic resonance imaging; diffusion-weighted imaging; prostate cancer; prostate-specific antigen
- From: Journal of Clinical Medicine in Practice 2024;28(24):26-30
- CountryChina
- Language:Chinese
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Abstract:
Objective To analyze the diagnostic efficacy of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) combined with diffusion-weighted imaging (DWI) in prostate cancer (PCa). Methods A total of 94 patients with prostate diseases were selected as study subjects, and divided into PCa group (
n =41) and benign prostatic hyperplasia (BPH) group (n =53). The general information of the two groups was compared. The diagnostic efficacy of DCE-MRI and DWI examination parameters in PCa and their correlation with serum prostate-specific antigen (PSA) were analyzed. Results There were statistically significant differences in total prostate-specific antigen (tPSA), free prostate-specific antigen (fPSA)/tPSA, prostate volume (V ), prostate-specific antigen density (PSAD), plasma volume fraction (V p), reflux rate constant (K ep), volume transfer constant (K trans), extracellular extravascular volume fraction (V e) and apparent diffusion coefficient (ADC) between the two groups (P < 0.05). The area under the curve for the combined prediction of PCa using DCE-MRI and DWI examination parameters was 0.924, which was greater than that for individual predictors or the combination of DCE-MRI examination parameters.K trans,K ep andV e were positively correlated with tPSA and negatively correlated with fPSA/tPSA, whileV p and ADC were negatively correlated with tPSA and positively correlated with fPSA/tPSA (P < 0.05). Conclusion The combination of DCE-MRI and DWI has high diagnostic value for predicting PCa, andK trans,K ep,V e,V p and ADC have certain correlations with tPSA and fPSA/tPSA.
