Research progress in Fangjiomics:methodologies,applications,and perspectives
10.1016/j.dcmed.2025.01.001
- VernacularTitle:方剂组学的研究进展:方法、应用与展望
- Author:
Bing LI
1
;
Yuwen ZHAO
;
Qikai NIU
;
Zhong WANG
Author Information
1. 中国中医科学院中药研究所,道地药材与品质保障全国重点实验室,北京 100700,中国;中国中医科学院中医临床基础医学研究所,北京 100700,中国
- Publication Type:Journal Article
- Keywords:
Fangjiomics;
Multi-omics data;
Compatibility of prescription;
Fangji database;
Network pharmacology
- From:
Digital Chinese Medicine
2024;7(4):309-319
- CountryChina
- Language:Chinese
-
Abstract:
Fangjiomics is a promising paradigm that enhances research on multi-omics-based pharma-cological mechanisms of Fangji from holistic and systematic perspective.We reviewed recent advances in Fangjiomics,focusing on database and analysis platform development,method-ological innovations,and translational applications.Through the integration of Fangji and multi-omics data,multi-level system analysis approaches were developed,encompassing single-target analysis,signaling pathways,multi-targeted network and modules.Fangjiomics has emerged as a key strategy in various areas of Fangji research.To support the high quality development of Fangjiomics,we propose principles and perspectives from the integrated,macro-level,and practical viewpoints.