Progress of research on the development of low-dose radiation biomarkers
10.13491/j.issn.1004-714X.2024.06.019
- VernacularTitle:低剂量辐射生物标志物的研究新进展
- Author:
Xin SUN
1
;
Yalin WANG
1
;
Qingjie LIU
1
;
Shuang LI
1
Author Information
1. China CDC Key Laboratory of Radiological Protection and Nuclear Emergency, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088 China.
- Publication Type:ReviewArticles
- Keywords:
Low-dose radiation;
Biomarker;
Biological dose estimation
- From:
Chinese Journal of Radiological Health
2024;33(6):728-734
- CountryChina
- Language:Chinese
-
Abstract:
With the widespread adoption of technologies such as diagnostic imaging, interventional medicine, radiotherapy, and nuclear medicine, a growing number of people are exposed to low-dose ionizing radiation. Currently, the biological effects of low-dose radiation remain unclear, necessitating the identification of sensitive and specific biomarkers for risk assessment and health monitoring of such exposure. In this paper, we review the latest research progress in low-dose ionizing radiation biomarkers from the five perspectives of cytogenetics, DNA damage, transcriptome, proteome, and metabolomics. This review aims to provide a theoretical basis for the study of the biological effects of low-dose radiation.
