Pathogenesis and Treatment Strategies of Tumor Angiogenesis Based on the Theory "Latent Wind in Collaterals"
10.13288/j.11-2166/r.2025.02.007
- VernacularTitle:基于“络脉伏风”探讨肿瘤血管生成的病机与治疗策略
- Author:
Zhenqing PU
1
;
Guibin WANG
2
;
Chenyang ZHANG
1
;
Yi LI
3
;
Bo PANG
3
;
Baojin HUA
3
Author Information
1. Beijing University of Chinese Medicine，Beijing，100029
2. Guangdong Provincial Hospital of Traditional Chinese Medicine
3. Guang'anmen Hospital，China Academy of Chinese Medical Sciences
- Publication Type:Journal Article
- Keywords:
tumors;
angiogenesis;
latent wind;
collaterals;
collateral disease
- From:
Journal of Traditional Chinese Medicine
2025;66(2):139-144
- CountryChina
- Language:Chinese
-
Abstract:
This article combined the pathogenic characteristics of "latent wind" with the theory of collateral diseases to clarify the pathological features of tumor blood vessels， including their active proliferation， high permeabi-lity， and promotion of metastasis. The theory framework of "latent wind in collaterals" as the tumor mechanism was proposed， which suggests that at the site of tumor lesions， the collaterals inherit the nature of latent wind to grow excessively， adopt an open and discharge nature to leak essence， and tumor toxins， characterized by their rapid movement and frequent changes， spread and metastasize， driving the progression of malignant tumors. Focusing on the fundamental pathogenesis of "latent wind in collaterals"， specific clinical treatment principles and methods centered on treating wind are proposed， including regulating qi and dispelling wind， clearing heat and extinguishing wind， unblocking collaterals and expelling wind， and reinforcing healthy qi to calm wind， so as to provide references for enhancing the precision of traditional Chinese medicine in treating malignant tumors.
