Herbal Textual Research and Modern Research Progress of Ostreae Concha
10.13422/j.cnki.syfjx.20250168
- VernacularTitle:牡蛎的本草考证及现代研究进展
- Author:
Hongyi ZHANG
1
;
Bin WANG
1
;
Jiawen LIU
1
;
Yuan HU
1
;
Lin CHEN
1
;
Youping LIU
1
;
Hongping CHEN
1
Author Information
1. School of Pharmacy，State Key Laboratory of Southwestern Chinese Medicine Resources， Chengdu University of Traditional Chinese Medicine，Chengdu 611137，China
- Publication Type:Journal Article
- Keywords:
Ostreae Concha;
herbal textual research;
historical evolution on processing;
quality control;
chemical composition;
pharmacological effect
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2025;31(3):223-234
- CountryChina
- Language:Chinese
-
Abstract:
By consulting relevant literature of ancient herbal books and processing specifications， this paper made a systematic research and analysis of Ostreae Concha， including the name， producing area， harvesting， quality， historical evolution of processing， relevant processing specifications， modern processing technology， and changes in chemical composition and pharmacological effects before and after processing， in order to provide documentary evidence for the research on processing technology and the establishment of quality standards. According to the textual research， it is known that Ostreae Concha has a long history of being used in medicine， and there have been many aliases and local names in each historical period. Shennong's Classic of the Materia Medica（Shennong Bencaojing） began to use Muli as the correct name， which has continued to use to today， and there were also aliases such as Muge， Zuogu Muli and Haoke. Ostreae Concha has a wide range of localities and irregular harvesting periods. The ancients believed that its left shell was of superior quality， but this has not been seen in modern. And there were many kinds of processing methods of Ostreae Concha， such as grinding， roasting， calcining， frying， simmering， quenching and so on， and the calcining was still in use. The different editions of Chinese Pharmacopoeia from 1963 to 2020 contain only calcined Ostreae Concha， and the local processing specifications mainly include three kinds of processed products（calcined products， salt-soaked products and vinegar-soaked products）. Modern processing research mainly focuses on process optimization， changes in chemical composition and pharmacological effects， and the research methods are relatively single. Overall， there are currently issues such as inconsistent processing standards， unclear process parameters and imperfect quality standards， which are not conducive to the quality control and standardized clinical use of Ostreae Concha. Therefore， it is necessary to further investigate the pharmacological substance basis of Ostreae Concha and its processed products in order to elucidate the processing mechanism， standardize the processing technology and improve the quality standard.
