Analysis of factors influencing macular edema in patients with diabetes cataract after surgery
10.3980/j.issn.1672-5123.2025.1.25
- VernacularTitle:糖尿病性白内障患者术后黄斑水肿的影响因素分析
- Author:
Ming LI
1
;
Fang XU
1
;
Zhijuan XU
1
Author Information
1. Department of Ophthalmology, Jiaozhou Central Hospital of Qingdao, Qingdao 266300, Shandong Province, China
- Publication Type:Journal Article
- Keywords:
diabetes cataract;
phacoemulsification;
cataract;
macular edema;
risk factors
- From:
International Eye Science
2025;25(1):140-143
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To explore the risk factors of macular edema in patients with diabetes cataract after surgery, and provide reference for postoperative prevention and treatment.METHODS: A total of 55 diabetes cataract patients(55 eyes)with macular edema after phacoemulsification surgery at the ophthalmology department of Jiaozhou Central Hospital of Qingdao from January 2022 to January 2024 were selected as edema group. In addition, 59 patients(59 eyes)with diabetes cataract who received the same surgical treatment but did not develop macular edema were treated as control group, and the relationship between interferon-induced protein-10(IP-10), macrophage chemotactic protein-1(MCP-1), vascular endothelial growth factor(VEGF)and postoperative macular edema was analyzed.RESULTS:Age, diabetes course, best corrected visual acuity(BCVA), glycated hemoglobin(HbA1c), creatinine, levels of IP-10, MCP-1 and VEGF in aqueous humor in the edema group were higher than those in the control group(all P<0.05). The risk factors for postoperative macular edema in patients with diabetes cataract were prolonged duration of diabetes, BCVA, increased HbA1c, increased creatinine and IP-10 in aqueous fluid, increased MCP-1 and increased VEGF(all P<0.05).CONCLUSION:Macular edema after surgical treatment in diabetes cataract patients is associated with prolonged duration of diabetes, BCVA, HbA1c, creatinine, IP-10, MCP-1, and VEGF, and clinical interventions should be given in advance.
