Two new isoflavones from Dalbergia rimosa Roxb.
10.16438/j.0513-4870.2023-1361
- VernacularTitle:多裂黄檀中两个新的异黄酮类化合物
- Author:
Wei-yu WANG
1
;
Wen-jiao CHEN
1
;
Mei-fang HUANG
1
;
Cheng-sheng LU
2
;
Xu FENG
1
;
Chen-yan LIANG
1
;
Jian-hua WEI
1
Author Information
1. College of Pharmacy, Guangxi University of Chinese Medicine, Nanning 530200, China; Teaching Center of Experiment and Practical Training, Guangxi University of Chinese Medicine, Nanning 530200, China; National Demonstration Center for Experimental Chinese Medicine Education, Guangxi University of Chinese Medicine, Nanning 530200, China
2. Teaching Center of Experiment and Practical Training, Guangxi University of Chinese Medicine, Nanning 530200, China; National Demonstration Center for Experimental Chinese Medicine Education, Guangxi University of Chinese Medicine, Nanning 530200, China; Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning 530011, China
- Publication Type:Research Article
- Keywords:
italic>Dalbergia rimosa Roxb.;
isoflavone;
albergiaisoflavone A;
albergiaisoflavone B;
antioxidant
- From:
Acta Pharmaceutica Sinica
2024;59(7):2053-2057
- CountryChina
- Language:Chinese
-
Abstract:
Studies on chemical constituents in the rhizome of Dalbergia rimosa Roxb. The chemical constituents from the ethyl acetate part of D. rimosa were isolated and purified by silica gel, MCI gel, Sephadex LH-20 gel and semi-preparative HPLC, and the stuctures were identified by spectral method. Thirteen compounds were isolated from the ethyl acetate part of the rhizome of D. rimosa and identified as dalbergiaisoflavones A, B (1, 2), formononetin (3), 7,4′-dimethoxyisoflavone (4), 4′,6,7-trimethoxyisoflavone (5), biochanin A (6), prunetin (7), 7-O-methyltectorigenin (8), 3′-hydroxydaidzein (9), orobol 7,3′-dimethyl ether (10), 2′,7-dihydroxy-4′,5′- dimethoxyisoflavone (11), pruinosanone E (12), caviunin (13). Compounds 1 and 2 are new compounds, and compounds 3-13 were isolated from this plant for the first time. Compounds 9 and 11 had remarkable scavenging effect on DPPH free radicals.
