Key issues in the study of drug nanocrystals self-stabilized Pickering emulsions as drug delivery system
10.16438/j.0513-4870.2023-1022
- VernacularTitle:药物纳米晶自稳定Pickering乳液给药系统研究的关键问题
- Author:
Ji-fen ZHANG
1
;
Fang-ming DONG
1
;
Chuan LIU
2
;
Tao YI
3
Author Information
1. College of Pharmaceutical Sciences, Southwest University, Chongqing 400716, China
2. Chengdu Institute of Food Inspection, Chengdu 611130, China
3. Faculty of Health Sciences and Sports, Macao Polytechnic University, Macao 999078, China
- Publication Type:Research Article
- Keywords:
Pickering emulsion;
rug delivery;
nanocrystal;
structure characteristic;
fate in vivo
- From:
Acta Pharmaceutica Sinica
2024;59(6):1582-1592
- CountryChina
- Language:Chinese
-
Abstract:
Drug nanocrystals self-stabilized Pickering emulsion (DNSPE) is a novel Pickering emulsion with drug nanocrystals as the stabilizer. There are more and more researches on DNSPE in the field of drug delivery in recent years. On the basis of summarizing the research status of DNSPE used as drug delivery systems, this paper comprehensively reviewed the research progress of three key issues, such as the main factors affecting construction of DNSPE, characterization methods of properties and structures, and in vivo fate, and looked forward to the industrialization prospect, which is beneficial to deepen the comprehensive research of DNSPE and promote its application in the field of drug delivery.
