Risk factors for death after one-stage radical surgery in children with interruption of aortic arch and ventricular septal defect
- VernacularTitle:主动脉弓中断合并室间隔缺损患儿一期根治术后死亡的危险因素分析
- Author:
Hailong SONG
1
;
Huijun ZHANG
1
Author Information
1. Department of Cardiac Surgery, First Hospital of Hebei Medical University, Shijiazhuang, 050000, P. R. China
- Publication Type:Journal Article
- Keywords:
Interruption of aortic arch;
ventricular septal defect;
left ventricular outflow tract obstruction;
cardiopulmonary bypass;
extracorporeal membrane oxygenation;
continuous renal replacement therapy;
risk factors
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2024;31(09):1300-1304
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors for death in children with interruption of aortic arch (IAA) and ventricular septal defect (VSD) after one-stage radical surgery. Methods A retrospective analysis was performed on patients with IAA and VSD who underwent one-stage radical treatment in the First Hospital of Hebei Medical University from January 2006 to January 2017. Cox proportional hazards regression model was used to analyze the risk factors for death after the surgery. Results A total of 152 children were enrolled, including 70 males and 82 females. Twenty-two patients died with a mean age of 30.73±9.21 d, and the other 130 patients survived with a mean age of 37.62±11.06 d. The Cox analysis showed that younger age (OR=0.551, 95%CI 0.320-0.984, P=0.004), low body weight (OR=0.632, 95%CI 0.313-0.966, P=0.003), large ratio of VSD diameter/aortic root diameter (VSD/AO, OR=2.547, 95%CI 1.095-7.517, P=0.044), long cardiopulmonary bypass time (OR=1.374, 95%CI 1.000-3.227, P=0.038), left ventricular outflow tract obstruction (LVOTO, OR=3.959, 95%CI 1.123-9.268, P=0.015) were independent risk factors for postoperative death. Conclusion For children with IAA and VSD, younger age, low body weight, large ratio of VSD/AO, long cardiopulmonary bypass time and LVOTO are risk factors for death after one-stage radical surgery.
