Mechanism of action and therapeutic potential of the Hippo signaling pathway in ocular disease
10.3980/j.issn.1672-5123.2024.11.14
- VernacularTitle:Hippo信号通路在眼部疾病中的作用机制和治疗潜力
- Author:
Liya DENG
1
;
Ying WANG
1
Author Information
1. Aier School of Ophthalmology, Central South University, Changsha 410015, Hunan Province, China
- Publication Type:Journal Article
- Keywords:
Hippo signaling pathway;
ocular diseases;
treatment
- From:
International Eye Science
2024;24(11):1764-1768
- CountryChina
- Language:Chinese
-
Abstract:
Hippo signaling pathway plays an important role in cell growth, proliferation, apoptosis, and stem cell regeneration. Dysregulation of this pathway has been linked to various diseases, such as cancer, heart disease, lung disease, kidney disease, liver disease, and immune dysfunction, as well as ocular diseases. Consequently, regulating the balance of Hippo signaling pathway may be an effective treatment for ocular diseases. This article reviews the mechanism of action and therapeutic potential of Hippo signaling pathway in ocular diseases, and discusses the potential therapeutic targets of the Hippo signaling pathway, to identify new targets and provide new research ideas for treating ocular diseases.
