A case of acute myocardial infarction associated with coronary vasospasm in a patient with systemic sclerosis.
- Author:
Chang Hun LEE
1
;
Na Rae KIM
;
Jong Sun PARK
;
Do Hyung KIM
;
Dong Hyun NO
;
Joon Hoon JEONG
;
Choong Won LEE
Author Information
1. Department of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea. jjhoon69@yahoo.co.kr
- Publication Type:Case Report
- Keywords:
Myocardial infarction;
Coronary vasospasm;
Systemic sclerosis
- MeSH:
Adult;
Blood Vessels;
Chest Pain;
Contracts;
Coronary Artery Disease;
Coronary Vasospasm;
Female;
Fibrosis;
Gastrointestinal Tract;
Heart;
Heart Diseases;
Humans;
Kidney;
Lung;
Musculoskeletal System;
Myocardial Infarction;
Necrosis;
Raynaud Disease;
Scleroderma, Systemic;
Skin;
Spasm
- From:Korean Journal of Medicine
2009;76(Suppl 1):S59-S63
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Systemic sclerosis is a chronic, systemic disease that targets the skin, lungs, heart, gastrointestinal tract, kidneys, and musculoskeletal system. Prominent features are vascular damage, immune activation, and the deposition of extravascular matrix. Scleroderma heart disease manifests as myocardial fibrosis. Intermittent spasm of the blood vessels in patients with systemic sclerosis may result in contraction band necrosis, similar to the changes observed in myocardial infarction in patients with atherosclerotic coronary artery disease. Coronary vasospasm has been demonstrated during attacks of cold-induced Raynaud's disease. However, acute myocardial infarction associated with coronary vasospasm in patients with systemic sclerosis has not been reported. We describe a rare case of acute myocardial infarction due to coronary vasospasm associated with systemic sclerosis in a 43-year-old woman who presented with severe chest pain.
