Safety evaluation of free bivalent human papilloma virus vaccine among junior middle school girls in Jiangxi Province
10.16835/j.cnki.1000-9817.2024272
- VernacularTitle:江西省初中女生免费接种二价人乳头瘤病毒疫苗安全性评价
- Author:
ZHAO Hongping, LIU Lihong, ZHENG Min, WU Fengyun, GUO Shicheng, LIU Jie
1
Author Information
1. Department of Immunization Program, Jiangxi Provincial Center for Disease Control and Prevention, Nanchang (330029) , Jiangxi Provinve, China
- Publication Type:Journal Article
- Keywords:
Papillomavirus vaccines;
Vaccination;
Students;
Female
- From:
Chinese Journal of School Health
2024;45(9):1251-1254
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the safety of free bivalent human papilloma virus (HPV) vaccine for junior middle school girls in Jiangxi Province, so as to provide the reference for HPV vaccination.
Methods:The number of free inoculation of bivalent HPV vaccine for junior middle school girls in Jiangxi Province from August 1, 2023 to May 31, 2024 were collected by Jiangxi Provincial Immunization Planning Information System, and the cases of adverse events following immunization (AEFI) were collected by China Disease Prevention and Control Information System. A descriptive analysis was conducted to assess the incidence of AEFI among middle school girls who received free bivalent HPV vaccine.
Results:Junior middle school girls in Jiangxi Province were vaccinated with free bivalent HPV vaccine for 1 061 023 doses, and 67 cases of AEFI were reported. Among the 67 cases, there were 50 cases of general reaction, 7 cases of abnormal reaction, 8 cases of psychogenic reaction and 2 cases of coupling syndrome. The reported incidence of AEFI, adverse reactions and psychogenic reactions were 6.31/100 000, 5.37/100 000 and 0.75/100 000 respectively. Adverse reactions were primarily general reactions (87.72%), with abnormal reactions counting for 12.28%. All AEFI cases were cured or improved, and no death or disability cases were reported.
Conclusion:The free vaccination of bivalent HPV for junior high school girls in Jiangxi Province is identified as highly safe, low adverse reaction reporting rate, and mainly general reactions, but attention should be paid to the prevention of psychogenic reactions in adolescents.
