Outcome analysis of assisted reproductive therapy in 126 patients with normal ovarian reserve after operation for benign ovarian tumors
10.19405/j.cnki.issn1000-1492.2022.10.030
- Author:
Wenjuan Xu
1
;
Xiaoqian Zhu
2
;
Jianye Wang
2
;
Ping Zhou
1
Author Information
1. Dept of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022;NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract , Anhui Medical University, Hefei 230032;Key Laboratory of Population Health Across Life Cycle , Anhui Medical University, Ministry of Education of the People s Republic of China , Hefei 230032
2. Dept of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022;Anhui Province Key Laboratory of Reproductive Health and Genetics , Anhui Medical University, Hefei 230032;Anhui Provincial Engineering Research Center of Biopreservation and Artificial Organs , Anhui Medical University, Hefei 230032
- Publication Type:Journal Article
- Keywords:
benign ovarian tumors;
ovarian reserve;
assisted reproductive therapy;
clinical outcomes
- From:
Acta Universitatis Medicinalis Anhui
2022;57(10):1675-1679
- CountryChina
- Language:Chinese
-
Abstract:
Objective :To explore the effects of surgical treatment for benign ovarian tumors on reproductive outcomes.
Methods :One hundred and twenty⁃six patients (case group) who underwent in vitro fertilization and intracytoplasmic sperm injection⁃embryo transfer (IVF/ICSI⁃ET) and a history of benign ovarian tumor surgery were retrospectively analyzed. Totally one hundred and forty patients who underwent IVF/ICSI⁃ET due to female tube factors during the same period were matched as control group. The general characteristics, the first controlled ovarian hyperstimulation (COH) process, clinical outcomes and cumulative reproductive outcomes were then compared.
Results :There was no significant difference in the general characteristics, total dosage of gonadotropin ( Gn)
used, duration of Gn used, estrogen (E2) level and intima thickness on human chorionic gonadotropin (HCG) in jection day during the first COH period between the two groups (P > 0. 05) . There was no significant difference in the number of oocytes retrieved, number of MII, follicle⁃oocyte index (FOI) and ovarian sensitivity index (OSI) (P > 0. 05) . However, the number of transferable embryos and high⁃quality embryos in control group was significantly higher than that in case group (P < 0. 05), while the transferred embryo number, implantation rate and clinical pregnancy rate were not statistically significant (P > 0. 05) . Moreover, the cumulative pregnancy rate and live birth rate, clinical pregnancy rate and live birth rate per transplant cycle, the number of oocytes retrieval cycles required per live birth, the number of transplant cycles required per live birth, and the number of embryos required per live birth were also not statistically significant between the two groups ( P > 0. 05 ) .
Conclusion :Compared with control group, the clinical outcomes of assisted reproductive therapy in benign ovarian tumors infertility patients with normal ovarian reserve after surgical treatment are not significantly different.
- Full text:2024081222001399140126例卵巢良性肿瘤术后卵...辅助生殖治疗的临床结局分析_徐文娟.pdf
