Research progress on the improvement mechanism of active ingredients of Swertia mussotii on metabolic syndrome
- VernacularTitle:藏茵陈有效成分改善代谢综合征的作用机制研究进展
- Author:
Tao WU
1
;
Li LIU
1
;
Hongping SONG
1
Author Information
1. Dept. of Pharmacy，Wuhan Fourth Hospital，Wuhan 430033，China
- Publication Type:Journal Article
- Keywords:
Swertia mussotii;
active ingredients;
metabolic syndrome;
obesity;
glucose and lipid metabolism;
mechanism of
- From:
China Pharmacy
2024;35(15):1928-1932
- CountryChina
- Language:Chinese
-
Abstract:
Metabolic syndrome （MS） is a complex group of clinical syndromes with obesity， abnormal glucose and lipid metabolism and hypertension as the main clinical features. Swertia mussotii is a commonly used medicine among the Tibetan people in China. Its efficacy is consistent with the pathogenesis of MS， which has the potential for symptomatic treatment of MS. It is found that effective ingredients such as gentiopicroside， sweroside， swertiamarin， mangiferin， and oleanolic acid can improve MS by regulating glucose and lipid metabolism， improving obesity， regulating the cardiovascular system， inhibiting chronic inflammation， oxidative stress， endoplasmic reticulum and autophagy， and improving intestinal microflora disorder.
