Research progress on HEG1 in cardiovascular generation and tumor development
10.3760/cma.j.cn112150-20230406-00261
- VernacularTitle:HEG1在心血管生成和肿瘤发生发展中的研究进展
- Author:
Yaoyao WANG
1
;
Xinjuan YU
;
Jiahui WANG
;
Qinghai LI
;
Wei HAN
Author Information
1. 青岛大学青岛市市立医院呼吸与危重症医学科,青岛 266071
- Keywords:
Heart development protein with EGF-like domains 1;
Cardiovascular system;
Neoplasms;
Diagnosis
- From:
Chinese Journal of Preventive Medicine
2024;58(1):136-140
- CountryChina
- Language:Chinese
-
Abstract:
Heart development protein with EGF-like domains 1 (HEG1) is a novel mucin-like membrane protein with a long O-glycosylation region and EGF domain. HEG1 plays critical roles in embryo development and cardiogenesis, and is closely related to the occurrence and progression of malignant tumors. Here this article demonstrates the research progress on HEG1 in cardiovascular formation and tumor development in recent years, to inspire new ideas for the pathogenesis, diagnosis and treatment of related diseases.