Surgical Experience of Infratentorial Meningiomas : Clinical Series at a Single Institution during the 20-Year Period.
10.3340/jkns.2014.55.6.321
- Author:
Min Ho JUNG
1
;
Kyung Sub MOON
;
Kyung Hwa LEE
;
Woo Youl JANG
;
Tae Young JUNG
;
Shin JUNG
Author Information
1. Department of Neurosurgery, Brain Tumor Clinic & Gamma Knife Center, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital & Medical School, Hwasun, Korea. moonks@chonnam.ac.kr
- Publication Type:Original Article
- Keywords:
Complication;
Intracranial meningioma;
Infratentorial;
Recurrence;
Surgical outcome;
Survival
- MeSH:
Edema;
Female;
Follow-Up Studies;
Humans;
Meningioma*;
Pathology;
Recurrence;
Retrospective Studies;
Skull Base;
Survival Rate
- From:Journal of Korean Neurosurgical Society
2014;55(6):321-330
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: Based on surgical outcomes of patients with infratentorial meningiomas surgically treated at our institution, we analyzed the predictors for surgical resection, recurrence, complication, and survival. METHODS: Of surgically treated 782 patients with intracranial meningioma, 158 (20.2%) consecutive cases of infratentorial location operated on between April 1993 and May 2013 at out institute were reviewed retrospectively. The patients had a median age of 57.1 years (range, 16--77 years), a female predominance of 79.7%, and a mean follow-up duration of 48.4 months (range, 0.8--242.2 months). RESULTS: Gross total resection (Simpson's grade I & II) was achieved in 81.6% (129/158) of patients. Non-skull base location was an independent factor for complete resection. The recurrence rate was 13.3% (21/158) and the 5-, 10-, and 15-year recurrence rates were 8.2%, 12.0%, and 13.3%, respectively. Benign pathology, postoperative KPS over than 90, low peritumoral edema, and complete resection were significantly associated with longer recurrence-free survival rate. The 5-, 10-, and 15-year survival rates were 96.2%, 94.9%, and 94.9%, respectively. Benign pathology, postoperative KPS over than 90 and complete resection were significantly associated with a longer survival rate. The permanent complication rate was 13% (21/158). Skull base location and postoperative KPS less than 90 were independent factors for the occurrence of permanent complication. CONCLUSION: Our experience shows that infratentorial meningiomas represent a continuing challenge for contemporary neurosurgeons. Various factors are related with resection degree, complications, recurrence and survival.
