Colletotrichum Jasminigenum-induced Infectious Sclerokeratitis: A Case Report
10.3341/jkos.2024.65.5.337
- Author:
In Seok JEONG
1
;
Woong Sun YOO
;
In Young CHUNG
;
Seong Wook SEO
;
Jung Hyun BYUN
;
Seong Jae KIM
Author Information
1. Department of Ophthalmology, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Korea
- Publication Type:Case Report
- From:Journal of the Korean Ophthalmological Society
2024;65(5):337-341
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Purpose:We present a case of Colletotrichum jasminigenum (C. jasminigenum)-induced Infectious sclerokeratitis.Case summary: An 81-year-old patient presented to our hospital with left eye pain and decreased vision that had started 7 days prior. He had a history of left eye pterygium excision a decade earlier. Examination using a slit lamp revealed a nasal conjunctival defect, scleral melting, deep stromal infiltration with a feathery margin, and hypopyon. Considering the suspicion of fungal sclerokeratitis, we performed a smear analysis and potassium hydroxide (KOH) and culture testing. The KOH test revealed hyphae, leading to systemic fluconazole and topical fluconazole and natamycin. Subsequently, we performed surgery, including debridement of the necrotic scleral area, conjunctival rotation and scleral grafting, and anterior chamber irrigation with intracameral and intravitreal voriconazole injections, due to progressive corneal infiltration and scleral melting. Additionally, we switched to using systemic and topical voriconazole. The culture yielded fungi, with DNA sequencing confirming C. jasminigenum as the causative agent. Following treatment, the lesion improved, and no signs of recurrence were observed.
Conclusions:Voriconazole is an effective treatment for C. jasminigenum-induced fungal sclerokeratitis.
