Clinical study of 13 patients with adult acute disseminated encephalomyelitis
- VernacularTitle: 13例成人急性播散性脑脊髓炎临床特点分析
- Author:
Fang LING
1
;
Qiming YANG
1
;
Heng JIANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Acute disseminated encephalomyelitis; Adult; Clinical characteristics; Treatment
- From: Journal of Apoplexy and Nervous Diseases 2021;38(3):242-244
- CountryChina
- Language:Chinese
- Abstract: ObjectiveExplore the clinical manifestation，neuro-imaging abnormalities，treatment and recovery of acute disseminated encephalomyelitis（ADEM）. Methods The clinical features 13 cases of ADEM were analyzed retrospectively. Results 11 cases（84.6%）had history of prodromic infection and 2 cases（15.4%）had history of vaccination. Clinical manifestations varied as 10 cases（76.9%）with fever，11 cases（84.6%）with headache，9 cases（69.2%）with disturbance of consciousness，9 cases（69.2%）with dyskinesia，5 cases（38.5%） with epileptic seizure；4 cases（30.7%）with cranial nerve injury，4 cases（30.7%）with incoordination；5 cases（38.5%）with mental and behavior disorder. MRI showed multiple abnormalities in head and spinal. All of the patients received glucocorticoid or human immunoglobulin therapy or plasmapheresis. During the 6 months-10 years of follow-up，10（76.9%）cases completely recovered and 3（23.0%）cases kept neurological deficits. Conclusion Adult ADEM characterized by acute onset，various clinical manifestations，and good prognosis. Timely diagnosis and treatment is recommended.
- Full text:202407301917102944Clinical study of 13 patients with adult acute disseminated encephalomyelitis.pdf
