Clinical and polysomnography findings in patients with Parkinson's disease with restless leg syndrome
10.19845/j.cnki.zfysjjbzz.2021.0086
- VernacularTitle:帕金森病伴不宁腿综合征患者多导睡眠图的临床特征研究
- Author:
Shuyu SUN
1
;
Jinxiang CHENG
;
Jian QIU
Author Information
1. 空军军医大学第二附属医院神经内科,陕西 西安 710038
- Publication Type:Journal Article
- Keywords:
Parkinson's disease;
Restless legs syndrome;
Polysomnography
- From:
Journal of Apoplexy and Nervous Diseases
2021;38(4):335-339
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the differences of clinical and sleep characteristics and related factors between patients with Parkinson's disease(PD)with restless leg syndrome(RLS)and idiopathic restless leg syndrome(iRLS).Methods One hundred and twenty-five patients with PD and 137 patients with iRLS from 2015 to 2020 were collected.PD patients were divided into PD with RLS group(PD-RLS)and PD without RLS group(PD-NRLS).The general condition,clinical features,subjective and objective sleep examination of the three groups were compared and analyzed.Results The prevalence of comorbid RLS in PD patients was27.2%.The score of UPDRS-Ⅲscore in patients with PD-RLS was higher than that in PD-NRLS.The objective sleep quality of patients with PD-RLS was worse than that of patients with iRLS.Age and comorbid PD were the risk factors of poor sleep quality in patients with RLS.IRLS-RS and HAMD scores are risk fac-tors for poor subjective sleep quality in patients with RLS.Conclusion Objective sleep disorders are more likely to occur in patients with PD-RLS than in patients with iRLS.While subjective sleep disorders in patients with iRLS are more severe.Which may be related to the clinical heterogeneity of RLS complicated with PD.
