Correlation between white matter lesions and cerebral microbleeds in lacunar infarction
10.19845/j.cnki.zfysjjbzz.2022.0031
- VernacularTitle:腔隙性脑梗死脑白质病变与脑微出血的相关性研究
- Author:
Wanchun LI
1
;
Yanli MENG
1
;
Zhiyuan SHAN
1
Author Information
1. Department of Neurology,Zhumadian Central Hospital,Zhumadian 463000,China
- Publication Type:Journal Article
- Keywords:
Lacunar infarction;
White matter lesions;
Cerebral microbleeds;
Relevance
- From:
Journal of Apoplexy and Nervous Diseases
2022;39(2):131-134
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between white matter lesions (WML) and cerebral microbleeds (CMBs) in patients with lacunar infarction (LI).Methods The clinical dataes from 129 patients with LI in our hospital were analyzed retrospectively.According to the severity of CMBs,the patients were divided into no bleeding group (n=20),mild group (n=60),moderate group (n=37) and severe group (n=12).The general data and laboratory results of patients in different groups were compared,the correlation between CMBs and white matter lesion scale (WMLs) was analyzed,the Logistic multivariate analysis was used to analyze the related factors of WML and CMBS in patients with LI.Results The age and the incidence of hypertension complication in patients with different CMBs were statistically significant (P<0.05).There were significant differences in serum HDL-C,LDL-C,hs-CRP,Hcy,CIMT levels and carotid plaque score in patients with different disease degrees of CMBs (P<0.05).Logistic regression analysis showed that age,hypertension,HDL-C,Hcy and CIMT were independent risk factors for the combined incidence of WML and CMBS in patients with LI (P<0.05).Conclusion The severity of WML in patients with LI is positively correlated with the degree of CMBs.The increase of age,history of hypertension,low-level HDL-C,high-level Hcy and CIMT are independent risk factors for the combined incidence of WML and CMBs in patients with LI.
- Full text:2024072611533169166Correlation between white matter lesions and cerebral microbleeds in lacunar infarction.pdf
