Comparative analysis of clinical features of benign and malignant thyroid nodules
10.3969/j.issn.1673-9701.2023.36.016
- VernacularTitle:良恶性甲状腺结节临床特征的比较分析
- Author:
Yonghao LI
1
;
Kai ZHANG
Author Information
1. 兰州大学第二医院核医学科,甘肃兰州 730030
- Keywords:
Thyroid nodules;
Thyroid function;
Ultrasonography;
Risk factors
- From:
China Modern Doctor
2023;61(36):68-71,77
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relevant risk factors of thyroid malignant tumor and provide basis for distinguishing the nature of thyroid nodules.Methods A total of 337 patients who underwent surgical treatment for thyroid nodules at the Second Hospital of Lanzhou University from June 2018 to January 2020 were selected,according to the pathological results,the patients were divided into benign nodule group and malignant nodule group.Clinical data of the two groups of patients were analyzed to explore the relevant risk factors for thyroid malignant tumors.Results ①The average age,longitudinal and transverse diameters of malignant nodule group were smaller than those of benign nodule group(P<0.001);②The proportion of patients with elevated serum thyrotropin(TSH),thyroglobulin antibody(TgAb),and thyroid peroxidase antibody(TPOAb)in malignant nodule group were higher than those in benign nodule group;The proportion of thyroglobulin(TG)elevation was lower than in benign nodule group(P<0.01);③The incidence of neck lymph node enlargement,low echogenicity within the nodule,nodule aspect ratio>1,irregular or irregular morphology,and unclear boundaries in malignant nodule group were higher than those in benign nodule group(P<0.05);④Binary Logistic regression analysis suggests that low echogenicity,calcification,irregular or irregular morphology,aspect ratio>1,and unclear or unclear boundaries were risk factors for malignant nodules;For every year of age increase,the incidence of malignant nodules decreases by 5.4%(P<0.05).Conclusion Ultrasound prompts low echo,calcification,irregular or irregular morphology,aspect ratio>1,and unclear or unclear boundaries are risk factors for thyroid cancer;Age is negatively correlated with the risk of thyroid cancer.
