Influence of diet intervention on BGP and bone mineral density (BMD) of patients with type 2 diabetes complicated with osteoporosis treated with alendronate
- VernacularTitle:饮食干预对阿仑膦酸钠治疗2型糖尿病合并骨质疏松患者骨钙素及骨密度的影响
- Author:
Xianghua ZHENG
1
;
Jun WANG
Author Information
1. 浙江省遂昌县中医院营养科
- Keywords:
Diet Intervention;
Type 2 diabetes;
Osteoporosis;
Bone mineral density (BMD);
BGP
- From:
China Modern Doctor
2014;(35):11-14
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss influence of diet intervention on BGP and bone mineral density(BMD) of patients with type 2 diabetes complicated with osteoporosis treated with alendronate. Methods A total of 80 cases of patients with type 2 diabetes complicated with osteoporosis were selected , and divided into intervention group and control group at random. The patients in two groups were given hypoglycemic or insulin injection to maintain the blood glucose concen-tration,and tested serum calcium concentration , and for patients with hypocalcemia were given calcium and alen-dronate 70 mg, one tablet per time, once a week ,with warm boiled water and empty stomach. The patients in control group were given routine diet,the patients in intervention group were given systematic diet intervention. The changes of BGP and BMD levels and VAS of patients in two groups before and 3 months after the medical treatment were observed and compared. Results The differences of BGP and BMD of patients in two groups before medical treatment had no statistical differences(P>0.05). After 3 months’ medical treatment, BGP and BMD levels of patients in two groups ob-viously rose than before,and the rising rate in intervention group was much higher than that in control group (P<0.05). Meanwhile, VAS of patients in two groups obviously declined than before , and the declining rate in intervention group was much higher than that in control group (P<0.05). Conclusion The application of reasonable diet intervention on patients with type 2 diabetes complicated with osteoporosis treated with Alendronate can improve the BMD and BGP levels, and lighten the pain symptom of patients.
