Effect of sevelamer hydrochloride combined hemodiafiltration on renal osteodystrophy
- VernacularTitle:盐酸司维拉姆联合血液透析滤过对肾性骨病的影响
- Author:
Meijuan XU
1
;
Jieying SHAO
Author Information
1. 广东省茂名市人民医院药剂科
- Keywords:
Renal osteodystrophy;
Sevelamer hydrochloride;
Hemodialysis
- From:
China Modern Doctor
2014;(18):45-47
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of sevelamer hydrochloride combined hemodiafiltration on renal os-teodystrophy. Methods A total of 69 cases with renal osteodystrophy were selected from July 2012 to November 2013 in our hospital, they were divided into three groups according to the treatment ,23 cases in each group, the control A group received sevelamer hydrochloride oral treatment, the control B group accepted hemodiafiltration, the treatment group received oral secretary hydrochloride and hemodiafiltration. The efficacy and common biochemical parameters before and after treatment of the three groups were compared. Results The total effective rate of the treatment group was significantly higher than that of the control A group and control B group, the difference was significant(P<0.05). The serum Ca levels of three groups after treatment were higher than before treatment, P, calcium-phosphorus product, ALP, β-MG, PTH were lower than before treatment, the difference was significant (P<0.05). Ca levels in the treatment group were higher than that in the control A group and control B group, P, calcium-phosphorus product, ALP, β-MG, PTH were lower than the control A group and control B group, the difference was significant(P<0.05). Conclusion Seve-lamer hydrochloride combined treatment of renal osteodystrophy hemodiafiltration obvious effect, can clinical applica-tion.
