Recent advance in relations of intestinal flora with autism spectrum disorders in children

VernacularTitle:肠道菌群与儿童自闭症谱系障碍关系的研究进展
Author: Rong ZOU ¹ ; Huajun ZHENG
Author Information

1. 复旦大学生殖与发育研究院，上海市计划生育科学研究所　200032
Keywords: Intestinal flora; Autism spectrum disorder; Children; Brain-intestine-bacteria axis
From: Chinese Journal of Neuromedicine 2020;19(3):320-324
CountryChina
Language:Chinese
Abstract: Autism spectrum disorder (ASD) is a serious neurodevelopmental disorder. Although its etiology and mechanism are still unclear, children with ASD often show gastrointestinal problems and immune disorders. Studies have shown that intestinal flora and its metabolites are not only associated with gastrointestinal problems, but also with autistic behavioral symptoms. In addition, maternal infections may increase the risk of ASD in offspring. This review focuses on the possible mechanism of intestinal flora influencing ASD and several possible methods related to intestinal flora for treatment of ASD in children, in order to provide new ideas for the treatment or prevention of autism children.