Recent advances in molecular markers and targeted therapy in glioblastoma
10.3760/cma.j.issn.1671-8925.2019.06.017
- VernacularTitle:胶质母细胞瘤中的分子标记物和靶向治疗的研究进展
- Author:
Qixue WANG
1
;
Kai ZHAO
;
Chunsheng KANG
Author Information
1. 天津医科大学总医院神经病学研究所
- Keywords:
Glioblastoma multiforme;
Molecular marker;
Target therapy
- From:
Chinese Journal of Neuromedicine
2019;18(6):629-633
- CountryChina
- Language:Chinese
-
Abstract:
Glioblastoma multiforme (GBM) is one of the most common invasive malignant tumors of the central nervous system.Molecular markers of glioblastoma are screened based on dataset,obtained through a large number of studies and algorithms,and could reflect the occurrence and development of GBM,or monitor the response to treatment.The molecular markers can effectively differentiate the subtypes,malignancy and response to radiotherapy of GBM.Here,we summarize the molecular markers of glioblastoma and discuss the prospects of targeted therapy for GBM.
