Review of drug utilization research based on real-world data
10.12206/j.issn.2097-2024.202312010
- VernacularTitle:基于真实世界数据的药物利用研究综述
- Author:
Yuanlin ZHANG
1
;
Kai SONG
;
Rui SUN
;
Fei SHU
;
Lixin SHU
;
Zhangwei YANG
Author Information
1. 中国人民解放军77570部队,西藏 昌都 854000;海军军医大学药学系军队药材保障论证中心,上海 200433
- Keywords:
real-world research;
drug utilization research;
rational drug use analysis;
real-world evidence;
real-world data
- From:
Journal of Pharmaceutical Practice and Service
2024;42(6):238-243
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,the rapid development of medical information technology has made it critical to analyze large-scale diagnosis and therapeutic data and extract rules based on real medical environment.This has become an essential approach for marketing evaluation and regulatory decision-making of drugs and devices both domestically and internationally.Real world study(RWS),as a novel methodology for clinical evaluation of drugs in the field of drug utilization research(DUR),have presented opportunities and challenges for observational studies in assessing actual efficacy or effectiveness.However,despite being a popular methodological approach among scholars in the field,there are still limitations and deficiencies when analyzing population medication characteristics in RWS.Systematic evaluation research methods have not yet been established,leading to inadequate generation of real-world evidence(RWE).The research design,methodological pathways,evaluation indicators,confounding factors,and bias management involved in DUR based on real-world data(RWD)were reviewed in this artical with the intention of providing guidance for further exploration into DUR.
